• Q&A FEATURES. Student-friendly Q&A features, interspersed throughout the text where questions naturally arise for students, help students learn key biochemistry concepts more efficiently and organically.
• MARGINAL GLOSSARY. Per student and faculty requests, the marginal glossary featured on each page makes it easier for students to learn key terms and understand concepts while reading the narrative.
• APPLY YOUR KNOWLEDGE BOXES. Interspersed within chapters, these boxes give students critical problem-solving experience.
• PROVEN IN-TEXT LEARNING AIDS. Concise summaries and a broad selection of problems and exercises, as well as an annotated bibliography at the close of each chapter, help students review and apply what they've learned.
• END-OF-CHAPTER PROBLEM SETS. The book's exceptionally strong and varied end-of-chapter questions are grouped by question type and include references to section numbers to help students prepare for exams.
• BIOCHEMICAL CONNECTION BOXES. These boxes demonstrate how biochemistry topics relate to the real world in such high-interest areas as allied health, sports medicine, and biotechnology.
• HOT TOPIC ARTICLES. Four NEW "Hot Topic" articles and five updated Hot Topics describe the latest advances in biochemistry and show students how biochemistry is relevant and important to our lives. Appearing at the end of select chapters where their relevance is immediately apparent, Hot Topic articles are also available online in the MindTap Reader, which features 9 articles describing exciting new developments in biochemistry. The Hot Topics are great to inspire in-class discussions or can be assigned for student presentations.
• ART and DESIGN PROGRAM. The book's vibrant, state-of-the art visual program has been revised to even better help students visualize key processes and understand important topics. The visual style and format of the art, a hallmark of the text, has been updated to better appeal to students and is designed to improve student learning outcomes.
• UPDATED COVERAGE. Each chapter in the text has been updated with the latest developments and scientific findings in the biochemistry field.
• NEW BIOCHEMICAL CONNECTIONS. Several new Biochemical Connections, integrated into the text, demonstrate how biochemistry topics relate to the real world in high-interest areas such as allied health, sports medicine, and biotechnology. These relevant content examples are meant to be read with the narrative, but they are specially written in a magazine-style voice that livens the narrative like crescendos to keep student interest at a high level and to show them how biochemistry is a part of them and their daily lives.
• BULLETED SUMMARIES. New bulleted summaries provide students with a more aesthetic at-a-glance review of the chapters that is more visually engaging.

1. Biochemistry and the Organization of Cells.

2. Water: The Solvent for Biochemical Reactions.

3. Amino Acids and Peptides.

4. The Three-Dimensional Structure of Proteins.

5. Protein Purification and Characterization Techniques.

6. The Behavior of Proteins: Enzymes.

7. The Behavior of Proteins: Enzymes, Mechanisms, and Control.

8. Lipids and Proteins Are Associated in Biological Membranes.

9. Nucleic Acids: How Structure Conveys Information.

10. Biosynthesis of Nucleic Acids: Replication.

11. Transcription of the Genetic Code: The Biosynthesis of RNA.

12. Protein Synthesis: Translation of the Genetic Message.

13. Nucleic Acid Biotechnology Techniques.

14. Viruses, Cancer and Immunology.

15. The Importance of Energy Changes and Electron Transfer in Metabolism.

16. Carbohydrates.

17. Glycolysis.

18. Storage Mechanisms and Control in Carbohydrate Metabolism.

19. The Citric Acid Cycle.

20. Electron Transport and Oxidative Phosphorylation.

21. Lipid Metabolism.

22. Photosynthesis.

23. The Metabolism of Nitrogen.

24. Integration of Metabolism: Cellular Signaling.

Answers.

Glossary.

Index.

Mary K. Campbell

Mary K. Campbell was Professor Emeritus of chemistry at Mount Holyoke College, where she taught biochemistry, general chemistry, and physical chemistry, as well as advised undergraduates working on biochemical research projects. Her avid interest in writing led to the publication of many highly successful editions of INTRODUCTION TO GENERAL, ORGANIC, AND BIOCHEMISTRY. She also coauthored BIOCHEMISTRY with Shawn O. Farrell. Originally from Philadelphia, Dr. Campbell received her Ph.D. from Indiana University and completed post-doctoral work in biophysical chemistry at Johns Hopkins University. Her areas of interest included researching the physical chemistry of biomolecules, specifically, spectroscopic studies of protein-nucleic acid interactions.

Shawn O. Farrell

Shawn O. Farrell, a native of Northern California, received his B.S. in biochemistry from University of California, Davis, studying carbohydrate metabolism. He completed his Ph.D. in biochemistry at Michigan State University, where he focused on the study of fatty acid metabolism. Dr. Farrell became interested in biochemistry while in college, as it was relevant to his passion for bicycle racing. He raced competitively for 15 years and now officiates bicycle races worldwide. He has taught biochemistry lecture and laboratory courses at Colorado State University for 19 years and now works for the Bicycle Racing Association of Colorado as its Executive Director. Professor Farrell has written scientific journal articles about specific research projects and about laboratory teaching, as well as articles for sports publications, such as "Salmon, Trout, and Steelheader" magazine. He is co-author with Mary Campbell on BIOCHEMISTRY, 4th through 8th editions (Cengage Learning); co-author with William Brown, Mary Campbell, and Omar Torres on GENERAL, ORGANIC, AND BIOCHEMISTRY; and author of EXPERIMENTS IN BIOCHEMISTRY: A HANDS ON APPROACH (Cengage Learning).

Owen M. McDougal

Owen M. McDougal is a professor of chemistry and biochemistry at Boise State University. A native of upstate New York, his love of the outdoors inspired him to travel west for graduate school and pursue a Ph.D. at the University of Utah in the laboratory of C. Dale Poulter. His work to elucidate the three-dimensional structures of neuropeptides by nuclear magnetic resonance spectroscopy involved the application of physical chemistry to address problems in biological systems. Upon completion of his Ph.D., Dr. McDougal sought an academic environment that allowed him to share his passion for science with students. He taught general, organic, and biological chemistry at Southern Oregon University which allowed him to hone his instructional skills. Looking to advance his love for writing, Owen shifted to a faculty position in the research-intensive environment at Boise State University, where he investigates the bioactivity of marine and terrestrial natural products, including studies of food chemistry, nutraceutical products, and specialty chemicals.